In 2016, there were 2.3 billion drinkers worldwide, and the hazardous use of alcohol cost 3 million lives globally, contributing to 5.3% of all fatalities as well as 132.6 million disability-adjusted life years (DALYs), or 5.1% of all DALYs in 2016. 1,2 So far, traditional pharmacotherapies such as acamprosate, naltrexone, disulfiram, and nalmefene have shown only moderate success in lowering…
