The Colorado river toad (Incilius alvarius) secretes 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT)1,2, a member of the class of psychoactive tryptamines that includes N,N-dimethyltryptamine (DMT), one of the main active components of ayahuasca.3 Structurally and functionally, 5-MeO-DMT and DMT are closely related, and may act as regulators of inflammation and neurogenesis through both 5…