Lysergic acid diethylamide (LSD) is being investigated for its potential therapeutic benefits for multiple neuropsychiatric disorders, including anxiety and depression.1,2 LSD produces its psychedelic effects (alterations in sensory perception and cognition) through activation of the serotonin 2A receptor (5-HT2AR),3 but LSD also has an affinity for other receptors in the serotonin and dopamine…